For some industries such as automotive, defence, aerospace, pharmaceutical manufacturing, dynamic pressure measurement is an important requirement. In a primary level dynamic pressure measurement system with a drop weight method, the dynamic pressure value is calculated using parameters such as the effective area value depending on the piston cylinder unit, the maximum acceleration value measured by a laser interferometer. On the other hand, the type of liquid used in the measuring head is another important factor affecting repeatability and providing ease of measurement. In this study, a new measurement head, piston and cylinders were designed, manufactured and the Taguchi method was used to accurately determine some parameters affecting the measurements in a dynamic primary pressure measurement system operating with the drop weight method. In the studies carried out, four pistons, four cylinders, four sampling frequency values and two liquid types were considered. By using the Taguchi method, the optimum parameters of the dynamic pressure measurement system with drop weight method were determined with only sixteen experiments instead of one hundred and twenty-eight.