Estimation and application of water retention curves in heavy soils have own specifics. The reason for these specific properties is the composition of the high clay texture. This is manifested by volume changes of soil depending on moisture. Up to 40% change in the volume compared to the saturated state was recorded in the conditions of the East Slovakian Lowland. The results described in this work are based on research work carried out in the East Slovakian Lowland and represent an analysis of selected 42 samples out of a total of 250 samples in which laboratory measurements of soil water retention curves and volume changes were performed. Selected samples represent the localities Senné and Poľany. Volumetric changes were measured in a laboratory by measuring the dimensions of soil samples. Appropriate changes in the volume of soil samples should be measured when determining moisture retention curves. Neglecting this physical effect leads to a distorted determination of the water retention curves in heavy soils. In the laboratory measurement of water retention curves points, changes in the volume of the sample were measured in the range of 0.24–43.67% depending on the soil moisture potential during drainage. In the case of neglecting the effect of shrinkage during the drainage of samples, a certain error is occurring in the calculation of the volumetric moisture. The range of this error was 1–13% of volumetric moisture.