The paper presents the two transmitter analog paths of 10 W and 400 W peak output power developed for micro- and macro-cell LTE450 base stations, respectively. Each path contains a chain of amplifiers with a final stage designed in the Doherty architecture to improve total transmitter power efficiency. The paths were optimized for linearity and efficiency considering, i.e., an output power vs. input power course shape and tuning of the amplifier's operating points while using low computational complexity MP algorithms.