Abstract
This work presents a simulation of the response of packets of microbubbles
in an ultrasonic pulse-echo scan line. Rayleigh-Plesset equation has been
used to predict the echo from numerically obtained radial dynamics of
microbubbles. Varying the number of scattering microbubbles on the pulse
wave form has been discussed. To improve microbubble-specific imaging at
high frequencies, the subharmonic and second harmonic signals from
individual microbubbles as well as microbubbles packets were simulated as
a function of size and pressure. Two different modes of harmonic
generation have been distinguished. The strength and bandwidth of the
subharmonic component in the scattering spectrum of microbubbles is
greater than that of the second harmonic. The pressure spectra provide
quantitative and detailed information on the dynamic behaviour of
ultrasound contrast agent microbubbles packet.
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