This paper presents the findings of fatigue strength tests of 15CrNi6 steel following low-pressure carburizing and oil quenching, subjected to cycles of one-sided three-point bending. The fatigue fractures were compared with the results of fatigue strength studies of 16MnCr5 steel following low-pressure carburizing and nitrogen quenching. The fatigue tests for 16MnCr5 steel were conducted as part of a high-cycle resonance test, with a pendular bending load. The study also involved an analysis of the effects on non-metallic inclusions in the structure on the mechanism of fatigue destruction. The inclusions were found to initiate fatigue cracks. In both cases, a similar method of a fatigue fissure initiation was observed, independent of the study method or specimen material.