The paper investigates the relations between Schwartz’s values and beliefs which may reflect skepticism toward science – specifically vaccine rejection, climate change denial and creationism. Recent research on the causes of anti-science indicates that they may be motivational, pertaining to ideologies, worldviews, and one’s moral codes. Therefore, we postulated that value priority hierarchies hierarchies may be predictors of anti-science. Results (N = 509) indicated that Conservation metatype values were positively associated with anti-science, while Self-Transcendence and Openness to change metatypes were connected with support for science. We also found significant differences in value profiles between participants with lower vs. higher anti-scientific beliefs. We discuss the possible motivational underpinnings of these results.