In the logistics center (warehouse or distribution center), customer orders need to be picked up by the pickers. In this research, we examine the order-picking problem with sequencedependent constraints with two decision variables (container start time and product quantity) in a distribution center with a one-directional conveyor. The decision-making is based on the developed two variations of two-step matheuristics. At first, the main order-picking problem is divided into two subproblems. Next, each step of each variant of the subproblem is solved using a mathematical programming-based technique. Both matheuristics were better in 85 of 120 test instances compared to the initial model solved by mathematical programming. Pickers matheuristics were better on average at 46.56%, while Buffers matheuristics were better on average at 46.87%. The proposed matheuristics approach allows distributors to schedule orders in the logistics center fast enough and with fewer resources.