@ARTICLE{Kocemba-Pilarczyk_Kinga_A._Molecular_2023,
 author={Kocemba-Pilarczyk, Kinga A. and Bentke-Imiolek, Anna and Dudzik, Paulina},
 volume={Vol. 63},
 number={No 2},
 journal={Folia Medica Cracoviensia},
 pages={135-148},
 howpublished={online},
 year={2023},
 publisher={Oddział PAN w Krakowie; Uniwersytet Jagielloński – Collegium Medicum},
 abstract={QF-PCR is a widely used molecular biology method. To name just a few of its uses, it is considered to be useful in paternity tests, identification tests or prenatal diagnostics. Therefore, there is a good chance that medical faculty students would come into contact with this technology — directly or indirectly — during their professional work. The following article proposes a teaching classes scenario conducted in the problem-based learning manner, which aims to familiarize students with the QF-PCR technique. In addition, other modern methods of molecular genetics are among topics that students can learn during the problem-based learning modules. The classes are divided into three parts. In the first part, students learn about the possible usage of QF-PCR in paternity tests. The second part focuses on learning about the advantages and limitations of QF-PCR in prenatal diagnosis. Learning activities in the last part are designed to show the limitations of the diagnostic properties of the method — students analyze the case study, in which QF-PCR must be replaced by other modern methods of molecular genetics. By analyzing three independent stories, students learn about usage, advantages and limitations of QF-PCR, and additionally gain knowledge in basic, pre-clinical and clinical sciences. This course is designated as an elective course for final year medical students who have completed either: a basic genetics course, a mo-lecular genetics course, a biochemistry course or a molecular biology course. The focus of the classes is to draw students’ attention to the possible application and rapid development of molecular biology techni-ques, which is the base for modern therapeutic and diagnostic strategies.},
 type={Article},
 title={Molecular biology techniques in real life — case study introducing medical students to QF-PCR technique used in medical diagnostics},
 URL={http://czasopisma.pan.pl/Content/129080/PDF-MASTER/2023-02-FMC-09.pdf},
 doi={10.24425/fmc.2023.145918},
 keywords={Problem Based Learning, medical education, QF-PCR, prenatal diagnostics, paternity tests, Next Generation Sequencing},
}