Aflatoonian R, Fazeli A (2008) Toll-like receptors in female reproductive tract and their menstrual cycle dependent expression. J Reprod Immunol 77: 7-13.

Aflatoonian R, Tuckerman E, Elliott SL, Bruce C, Aflatoonian A, Li TC, Fazeli A (2007) Menstrual cycle-dependent changes of Toll-like receptors in endometrium. Hum Reprod 22: 586-593.

Akashi S, Shimazu R, Ogata H, Nagai Y, Takeda K, Kimoto M, Miyake K (2000) Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J Immunol 164: 3471-3475.

Akira S (2003) Toll-like receptor signaling. J Biol Chem 278: 38105-38108.

Arici A, Tazuke SI, Attar E, Kliman HJ, Olive DL (1996) Interleukin-8 concentration in peritoneal fluid of patients with endometriosis and modulation of interleukin-8 expression in human mesothelial cells. Mol Hum Reprod 2: 40-45.

Arosh JA, Banu SK, Chapdelaine P, Madore E, Sirois J, Fortier MA (2004) Prostaglandin biosynthesis, transport, and signaling in corpus luteum: a basis for autoregulation of luteal function. Endocrinology 145: 2551-2560.

Atli MO, Akbalık ME, Kose M, Alak I, Atli Z, Hitit M (2022) Expression pattern and cellular localization of two critical non-nuclear progesterone receptors in the ovine corpus luteum during the estrous cycle and early pregnancy. Anim Reprod Sci 243: 107026.

Atli MO, Bender RW, Mehta V, Bastos MR, Luo W, Vezina CM, Wiltbank MC (2012) Patterns of gene expression in the bovine corpus luteum following repeated intrauterine infusions of low doses of prostaglandin F2alpha. Biol Reprod 86: 130.

Atli MO, Kose M, Hitit M, Kaya MS, Bozkaya F (2018) Expression patterns of Toll-like receptors in the ovine corpus luteum during the early pregnancy and prostaglandin F2α-induced luteolysis. Theriogenology 111: 25-33.

Atli MO, Köse M, Kaya MS, Aydilek N, Güzeloğlu A, Wiltbank MC (2017) Toll-like receptor 2 and 4 expression in the bovine corpus luteum during the different stages of the estrous cycle. Anim Reprod 14 : 1270-1277.

Bazzocchi C, Mortarino M, Comazzi S, Bandi C, Franceschi A, Genchi C (2005) Expression and function of Toll-like receptor 2 in canine blood phagocytes. Vet Immunol Immunopathol 104: 15-19.

Bednarz-Misa I, Neubauer K, Zacharska E, Kapturkiewicz B, Krzystek-Korpacka M (2020) Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR. Adv Clin Exp Med 29: 547-556.

Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55: 611-622.

Chotimanukul S, Sirivaidyapong S (2011) Differential expression of Toll-like receptor 4 (TLR4) in healthy and infected canine endometrium. Theriogenology 76: 1152-1161.

Chotimanukul S, Sirivaidyapong S (2012) The localization of Toll‐like Receptor 2 (TLR 2) in the endometrium and the cervix of dogs at different stages of the oestrous cycle and with pyometra. Reprod Domest Anim 47: 351-355.

Crozat K, Beutler B (2004) TLR7: A new sensor of viral infection. Proc Natl Acad Sci U S A 101: 6835-6836.

Du M, Wang X, Yue YW, Zhou PY, Yao W, Li X, Ding XB, Liu XF, Guo H, Ma WZ (2016) Selection of reference genes in canine uterine tissues. Genet Mol Res 15: 15028138.

Gadsby JE, Tyson Nipper AM, Faircloth HA, D’Annibale‐
-Tolhurst M, Chang J, Farin PW, Sheldon IM, Poole DH (2017) Toll‐like receptor and related cytokine mRNA expression in bovine corpora lutea during the oestrous cycle and pregnancy. Reprod Domest Anim 52: 495-504.

Hagman R (2018) Pyometra in small animals. Vet Clin North Am Small Anim Pract 48: 639-661.

Hoffmann B, Riesenbeck A, Klein R (1996) Reproductive endocrinology of bitches. Anim Reprod Sci 42: 275-288.

Jiemtaweeboon S, Shirasuna K, Nitta A, Kobayashi A, Schuberth HJ, Shimizu T, Miyamoto A (2011) Evidence that polymorphonuclear neutrophils infiltrate into the developing corpus luteum and promote angiogenesis with interleukin-8 in the cow. Reprod Biol Endocrinol 9: 79.

Johnston SD, Kustritz MR, Olson PNS (2001) Disorders of the canine uterus and uterine tubes (oviducts). In: Johnston SD, Kustritz MR, Olson PNS (eds) Canine and Feline Theriogenology. Philadelphia, WB Saunders pp 463-471.

Jungi TW, Farhat K, Burgener IA, Werling D (2011) Toll-like receptors in domestic animals. Cell Tissue Res 343: 107-120.

Kannaki TR, Shanmugam M, Verma PC (2011) Toll-like receptors and their role in animal reproduction. Anim Reprod Sci 125: 1-12.

Kawai T, Akira S (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.

Kaya MS, Kose M, Guzeloglu A, Kıyma Z, Atli MO (2017) Early pregnancy-related changes in toll-like receptors expression in ovine trophoblasts and peripheral blood leukocytes. Theriogenology 93: 40-45.

Kempisty B, Bukowska D, Wozna M, Piotrowska H, Jackowska M, Zuraw A, Ciesiolka S, Antosik P, Maryniak H, Ociepa E, Porowski SZ, Brussow KP, Jaskowski JM, Nowicki M (2013) Endometritis and pyometra in bitches: a review. Vet Med-Czech 58: 289-297.

Kida K, Baba E, Torii R, Kawate N, Hatoya S, Wijewardana V, Sugiura K, Sawada T, Tamada H, Inaba T (2006) Lactoferrin expression in the canine uterus during the estrous cycle and with pyometra. Theriogenology 66: 1325-1333.

Koch AE, Polverini PJ, Kunkel SL, Harlow LA, DiPietro LA, Elner VM, Elner SG, Strieter RM (1992) Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 258: 1798-1801.

Kowalewski MP (2014) Luteal regression vs. prepartum luteolysis: regulatory mechanisms governing canine corpus luteum function. Reprod Biol 14: 89-102.

Kowalewski MP, Fox B, Gram A, Boos A, Reichler I (2013) Prostaglandin E2 functions as a luteotrophic factor in the dog. Reproduction 145: 213-226.

Kowalewski MP, Mason JI, Howie AF, Morley SD, Schuler G, Hoffmann B (2006) Characterization of the canine 3beta-hydroxysteroid dehydrogenase and its expression in the corpus luteum during diestrus. J Steroid Biochem Mol Biol 101: 254-262.

Kundakci A, Pirat A (2012) Toll-Like Receptors. J Turk Soc Intens Care 10: 63-73.

Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408.

Lüttgenau J, Herzog K, Strüve K, Latter S, Boos A, Bruckmaier RM, Bollwein H, Kowalewski MP (2016) LPS-mediated effects and spatio-temporal expression of TLR2 and TLR4 in the bovine corpus luteum. Reproduction 151: 391-399.

Magata F, Ishida Y, Miyamoto A, Furuoka H, Inokuma H, Shimizu T (2015) Comparison of bacterial endotoxin lipopolysaccharide concentrations in the blood, ovarian follicular fluid and uterine fluid: a clinical case of bovine metritis. J Vet Med Sci 77: 81-84.

Nitsche JF, Jiang SW, Brost BC (2010) Toll‐like receptor‐2 and Toll‐like receptor‐4 expression on maternal neutrophils during pregnancy. Am J Reprod Immunol 64: 427-434.

Nowak M, Aslan S, Kowalewski MP (2020) Determination of novel reference genes for improving gene expression data normalization in selected canine reproductive tissues – a multistudy analysis. BMC Vet Res 16: 440.

Papa PC, Kowalewski MP (2020) Factors affecting the fate of the canine corpus luteum: Potential contributors to pregnancy and non-pregnancy. Theriogenology 150: 339-346.

Pate JL, Johnson‐Larson CJ, Ottobre JS (2012) Life or death decisions in the corpus luteum. Reprod Domest Anim 47: 297-303.

Patra MK, Kumar H, Nandi S, Loyi T, Islam R (2014) Upregulation of TLR-4 and proinflammatory cytokine transcripts as diagnostic indicator of endometritis in buffaloes. J Appl Anim Res 42: 256-262.

Penny LA (2000) Monocyte chemoattractant protein 1 in luteolysis. Rev Reprod 5: 63-66.

Pfaffl MW, Tichopad A, Prgomet C, Neuvians TP (2004) Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper-Excel-based tool using pair-wise correlations. Biotechnol Lett 26: 509-515.

Piccinini AM, Midwood KS (2010) DAMPening inflammation by modulating TLR signalling. Mediators Inflamm 2010: 672395.

Piehler AP, Grimholt RM, Ovstebø R, Berg JP (2010) Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes. BMC Immunol 11: 21.

Polec A, Tanbo T, Fedorcsak P (2009) Cellular interaction regulates interleukin‐8 secretion by granulosa‐lutein cells and monocytes/macrophages. Am J Reprod Immunol 61: 85-94.

Santana CH, Santos RL (2021) Canine pyometra-an update and revision of diagnostic terminology. Braz J Vet Pathol 14: 1-8.

Schlafer DH, Gifford AT (2008) Cystic endometrial hyperplasia, pseudo-placentational endometrial hyperplasia, and other cystic conditions of the canine and feline uterus. Theriogenology 70: 349-358.

Shirasuna K, Jiemtaweeboon S, Raddatz S, Nitta A, Schuberth HJ, Bollwein H, Miyamoto A (2012) Rapid accumulation of polymorphonuclear neutrophils in the corpus luteum during prostaglandin F(2α)-induced luteolysis in the cow. PLoS One 7: e29054.

Shirasuna K, Matsumoto H, Matsuyama S, Kimura K, Bollwein H, Miyamoto A (2015) Possible role of interferon tau on the bovine corpus luteum and neutrophils during the early pregnancy. Reproduction 150 : 217-225.

Silva E, Henriques S, Brito S, Ferreira-Dias G, Lopes-da-Costa L, Mateus L (2012) Oestrous cycle-related changes in production of Toll-like receptors and prostaglandins in the canine endometrium. J Reprod Immunol 96: 45-57.

Silva E, Leitao S, Henriques S, Kowalewski MP, Hoffmann B, Ferreira-Dias G, Lopes da Costa L, Mateus L (2010) Gene transcription of TLR2, TLR4, LPS ligands and prostaglandin synthesis enzymes are up-regulated in canine uteri with cystic endometrial hyperplasia-pyometra complex. J Reprod Immunol 84: 66-74.

Skarzynski DJ, Okuda K (2010) Inter- and intra-cellular mechanisms of prostaglandin F2alpha action during corpus luteum regression in cattle. Soc Reprod Fertil Suppl 67: 305-324.

Smith FO (2006) Canine pyometra. Theriogenology 66: 610-612.

Stocco C, Telleria C, Gibori G (2007) The molecular control of corpus luteum formation, function, and regression. Endocr Rev 28: 117-149.

Stocco DM (2001) StAR protein and the regulation of steroid hormone biosynthesis. Annu Rev Physiol 63: 193-213.

Sugiura K, Nishikawa M, Ishiguro K, Tajima T, Inaba M, Torii R, Hatoya S, Wijewardana V, Kumagai D, Tamada H, Sawada T, Ikehara S, Inaba T (2004) Effect of ovarian hormones on periodical changes in immune resistance associated with estrous cycle in the beagle bitch. Immunobiology 209: 619-627.

Takeuchi O, Akira S (2010) Pattern recognition receptors and inflammation. Cell 140: 805-820.

Ucar EH, Cetin H, Atli MO (2018) Effect of multiple low-dose PGF2α injections on the mature corpus luteum in non-pregnant bitches. Theriogenology 113: 34-43.

Ucar EH, Peker C, Hitit M, Kose M, Tatar M, Bozkaya F, Atli MO (2024) Altered luteal expression patterns of genomic and non-genomic progesterone receptors in bitches at different reproductive states. Theriogenology 218: 153-162.

Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.

Wang D (2008) Discrepancy between mRNA and protein abundance: insight from information retrieval process in computers. Comput Biol Chem 32: 462-468.

Yoo I, Han J, Lee S, Jung W, Kim JH, Kim YW, Kim HJ, Hong M, Ka H (2019) Analysis of stage-specific expression of the toll-like receptor family in the porcine endometrium throughout the estrous cycle and pregnancy. Theriogenology 125: 173-183.

Zähringer U, Lindner B, Inamura S, Heine H, Alexander C (2008) TLR2–promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity. Immunobiology 213: 205-224.